The Center was established as a result of the institutionalization of the activities initiated under the Central Asia Drug Action Programme (CADAP). This program is funded by the European Union, was designed to help in the further development of effective and comprehensive drug policy in Central Asia. The participation of Kazakhstan specialists in the component DAMOS of CADAP Programme was a key in creating a Monitoring Centre on Alcohol and Drugs in the Republic of Kazakhstan. Under component DAMOS complex aspects of the drug situation in Central Asia were monitored, institutionalized collection and analysis of indicators of the drug situation in the field of drug demand and supply of drugs were done, and stable drug information system, an effective system of reporting in the national and international organizations were developed. The joint publication of the European Monitoring Centre on Drugs and Drug Addiction and the Inter-American Commission for Drug Abuse Control of the Organization of American States, considering the creation of the National Observatory on Drugs (see http://www.emcdda.europa.eu/publications/joint/ndo-handbook) has made a great contribution to development of the Monitoring Centre on Alcohol and Drugs in the Republic of Kazakhstan.